| Number | Base of difference | Express JS Framework | Fastify Web Framework |
| 1 | Performance | Well when we say about the Express JS Framework, it is widely used framework due to its performance but is not in performance as of Fastify Framework. | When we say about the Fastify Web Framework it is designed for high performance. And this claimed it is one of the fastest framework in Node.js. |
| 2 | Validation | When we say about the Express JS, it relies on middleware or custom code for input validation. | When we say about the Fastify Framework it has built in support for JSON schema validation. |
| 3 | Dependency Injection | When we say about the Express JS, this will requires external libraries for implementing depdendency injection. | When we say about the Fastify Web framework, this has the built in dependency injection system. |
| 4 | Integration | When we say about the Integration, here developer can choose and integrate various components. | And when we say about the Fastify Web Framework it offers flexibility with guided approach. |
| 5 | Community
| When we say about the community for Express JS, this has large well established community with broad eco-system of middleware of tools. | When we say about the community Fastify has growing community for eco system. |